1. Mrs. Smith is a 75-year-old woman presenting to the emergency department with complaints of burning on urination and urinary frequency. She has a past medical history of hypertension, atrial fibrillation, and osteoarthritis. Her medications include hydrochlorothiazide, lisinopril, and warfarin. She has no known drug allergies. You perform a urinalysis which is remarkable for nitrites and greater than 25 WBC per high powered field. Which treatment regimens would be contraindicated? Select all that apply
2. Mr. Roberts is a 66-year-old man with a history of gout who presents with a two-day history of right great toe pain. He also has a past medical history of renal insufficiency but his most recent creatinine level (one week ago) was 120 mmol/L. On physical exam, his vital signs are stable. His estimated weight is 70kg. Your physical exam findings are consistent with a diagnosis of acute gouty arthritis. Which treatment regimens would be contraindicated? Select all that apply
3. You are prescribing a medication for an 80-year-old man with an estimated weight of 65kg and a creatinine of 90 mmol/L. The medication you have selected is primarily eliminated by the kidneys. What medication adjustments should be considered?
4. A 70 year-old man presents with neck pain and stiffness after a motor vehicle accident sustained the day before. After a thorough evaluation, you diagnose the patient with neck strain. His most recent creatinine level (one week ago) was 80 mmol/L. His only medical history is osteoarthritis. He takes no medications. Which medications would be appropriate for symptomatic relief? Select all that apply
5. Gabapentin and amitriptyline are equally appropriate choices for the treatment of post-herpetic neuralgia.